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Activation of p53 by Novel MDM2 Antagonist RG7388 Overcomes AML Inherent and Acquired Resistance to Bcl-2 Inhibitor ABT-199 (GDC-0199)

Heneka et al., 2025)

doi: 10.3233/JAD-160926 132

PLoS Pathog 8(5):e1002708 Cook LE, Locke MC, Young AR, Monte K, Hedberg ML, Shimak RM et al (2019) Distinct roles of interferon alpha and beta in controlling Chikungunya virus replication and modulating neutrophil-mediated inflammation

this special approach of compatibility has achieved the effect of enhancing the curative effect and reducing the toxic and side-effects, for example, with the use of drugs such as ligustrazine hydrochloride injection, tranquilizing and antiepileptic prescription, wild jujube seed decoction, and gastrodin injection

also suggests that the peptide may upregulate VEGF, increase endothelial cell proliferation, and promote endothelial migration and tube formation