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In obese mice, chronic administration of AOD-9604 was shown to significantly increase 3- adrenergic receptor (3-AR) mRNA expression in both white and brown adipose tissue

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At the end of the study, six of the ten MVD-affected dogs being fed the CNB-laced kibble showed modest improvements in their heart measurements, while one of those dogs progressed to severe mitral regurgitation

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[Crossref] [PubMed] Qiu G, Zhang L, Gu Z, et al