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ROS cause oxidative damage to various cellular components and disrupt the balance between ECM catabolism and anabolism 119

Firmer and Lifted Skin / Improve Skin Strength and Elasticity

doi: 10.1016/j.isci.2023.107487 126 ChoiSLiWZhangXKandaNLeilaniZTengXet al

Nrf2, which can induce the expression of phase II detoxifying enzyme-encoding genes through antioxidant response elements (AREs), was defined as a master regulator of antioxidant systems in 1997