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Si le diagnostic n'est pas vident, avec une macrocytose faible (volume globulaire moyen de 100 105 3 ), il faut liminer une insuffisance rnale chronique, une inflammation chronique, une hypothyrodie, un thylisme patent, avant de faire un mylogramme

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[17] Postmarketing reports have associated intravenous hydroxocobalamin therapy when used as a cyanide antidote with the development of renal impairment and crystalluria with hemodialysis being necessary in some cases for recovery

This presents a meaningful clinical concern, particularly in populations exposed to polypharmacy or managing complex comorbidities

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