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This result highlights the utility of BIVID-MaP in discovering variant-specific RNA structure-small molecule interactions that are difficult to predict solely from sequence information

Results Characterization of repRNA encoded gH/gL and gH/gL/gp42 To enable co-delivery of both gH and gL or gH, gL, and gp42 on a single repRNA, we designed two constructs

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The valine backbones of GRXC2 and ROXY9 cannot be perfectly superimposed due to the different positioning of the loop in the two proteins

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors

239 Inhibiting p38MAPK activation has been found to reduce the CS-induced airway smooth muscle cell proliferation, 240 suggesting that p38MAPK inhibitors may reduce the progression of COPD airway remodelling