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Wang DY, Done SJ, Mc Cready DR, Leong WL

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We also demonstrate that SCLC cells associated with high ASCL1 expression are more susceptible to the blockage of mitochondrial respiratory complex I (NADH dehydrogenase) and, moreover, that non-ASCL1-driven cells are more susceptible to glutaminolysis inhibition, which may allow future subtype-specific personalized therapy

Furthermore, the pathogenesis of hypertension has been linked to oxidative stress, which is characterized as an imbalance between oxidants and antioxidants that favors oxidant-induced damage (7)