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Although thioredoxin is not itself imported into the ER (being an 11.6 kDa protein rather than a small tripeptide like glutathione), the pathway has been shown to influence ER lumenal redox potential, likely through the conveyance of reducing equivalents through an as-yet unknown ER-resident transmembrane protein (Poet et al., 2017)

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Consult a Healthcare Provider: If you suspect you have a vitamin B12 deficiency or are considering supplementation, it's important to consult a healthcare professional for proper evaluation and guidance

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High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: A systematic review and meta-analysis