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178 Phosphorylated CREB inhibits NF-B activation by competing with p65 for binding to CREB-binding protein (CBP)

doi: 10.1104/pp.94.3.1496 75 SawakeS.TajimaN.MortimerJ

Remarkably, abrogation of the K133:D129 electrostatic interaction (IL-1 K133A and IL-1 D129A point mutations) increased IL-1 stability even further (Fig