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Description

However, if the UPR fails to resolve the excessive buildup of unfolded proteins, it activates signaling pathways that promote inflammation and apoptosis, potentially leading to neurodegenerative disorders

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For experiments in 6-well plates, 50,000 cells were seeded, and after 24 hours, the medium was aspirated and washed once with PBS, and the indicated medium was added

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Compared to the control group, the total effective rate in the treatment group was significantly higher ( P = .029), as shown in Table 2

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Endo, Y

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These results complement earlier studies showing anti-oxidant effect of MSM and suggest that single dose oral supplementation with MSM lowers exercise induced oxidative stress in healthy untrained young men, but is not adequate to significantly affect plasma GSH level

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