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For experiments involving oxygen control, purified CD8 + T cells were immediately acclimatized to the required oxygen tension (21%, 5% or 1% O 2 ) for 2 h in complete RPMI 1640 supplemented with 10% FBS, 100 U ml 1 penicillin and 100 g ml 1 streptomycin, before activation with anti-CD3/CD28 Dynabeads and 30 U ml 1 IL-2

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Although there are clinical trials for spontaneous cerebral hemorrhage removal, there are still no clinical trials specifically for TICH hematoma removal (Table 1)

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and J.S.), a NHLBI grant K08HL145132 (J.S.), and a AHA pre-doctoral fellowship award 20PRE35120060 (H.W.)