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Medium-chain fatty acids may play a central role in the KD, which may regulate mitochondrial metabolism in astrocytes and have positive effects on the brain such as accelerated glycolysis, enhanced lactate shuttle, and accelerated ketone body production (190)

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Data were synthesized to produce two outputs: a provider-facing summary of clinical recommendations and a patient-facing educational brochure

Clinical evidence and limitations 5.1

Start with five days of supplementation followed by two days off

Tumor cells selectively take up more vitamin C compared to normal cells through an upregulated metabolic need for glucose due to similarities between Vitamin C and Glucose (Agus 1997)