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Bortfeld T, Schlegel W, Dykstra C, Levegrun S, Preiser K, Mohan R , Wang X

211 This process helps maintain the cytosolic level of NAD + , thus contributing to the continuity of glycolysis

On the other hand, exosomes from cells with reparative potential, such as bone marrow mesenchymal stem cells (MSCs) or amniotic epithelial cells, have been found to downregulate the pro-ferroptotic lipid metabolism enzyme ACSL4, or upregulate parallel anti-ferroptosis pathways like FSP1/GPX4, thereby attenuating ferroptosis and promoting cartilage repair (Wang Y