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doi: 10.3389/fendo.2020.570628 129 HofP

The co-culture system established with MCECs and MPMs is shown in Figure 4D

Accessed February 24, 2012

doi:10.3389/fmicb.2015.00742

Chen JX, Yan SD

PPAR binds to the LC3 promoter, thus increasing its expression, activates BNIP3-mediated mitophagy, induces apoptosis, and inhibits the accumulation of fat ( in vitro obesity model established using mouse preadipocyte (3T3-L1) differentiation, and increased NR1D1 could rapidly bind to the ULK1 promoter, thus significantly up-regulating the expression of ULK1, Parkin and PINK1 and down-regulating that of TOM20, increasing mitophagy levels, enhancing 3T3-L1 cell viability and triglyceride (TG) content, reducing lipid droplet production, and attenuating obesity