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is supported by an MRC Skills Development Fellowship award (MR/S019332/1)

Statistical analyses show that the frequency of the null genotype was not significantly higher in the group of patients with nephropathy than in the group of patients without nephropathy, suggesting that the null genotype does not contribute to the development of DN in this population [59]

Additionally, the development of pharmacological agents that precisely modulate intracellular iron homeostasis, such as iron chelators or iron oxide NPs, or enhance iron bioavailability specifically within the TME, may facilitate the targeted exploitation of ferroptosis pathways

doi: 10.1038/sj.leu.2403610

M., & Palsson, B