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Symposium on Myelodysplastic Syndromes: Biology and Treatment, Houston, 1988

0.5 g (0.35 mmol) of a pentadecapeptide with the sequence Gly Glu Pro Pro Pro Gly Lys Pro Ala Asp Asp Ala Gly Leu Val (BPC157) was dissolved in 10 ml water containing 29,6 mg of sodium hydrogencarbonate (0.35 mmol), sterile filtered through a 0.2 filter and dried by freeze-drying to give 0.48 g of an off-white solid

In turn, biopsy of skin lesions showed superficial epidermal necrosis with dyskeratotic keratinocytes

R.HoldenH.et al (2005)

Microbiology 148 , 507518 (2002)

BPC-157s anti-inflammatory mechanism primarily through NO pathway modulation and reduced pro-inflammatory cytokine expression produces meaningful analgesic effects without the GI side effects associated with NSAIDs