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In preclinical studies, NTZ suppresses intracellular M.tb proliferation by inhibiting the enzymatic activity of human quinone oxidoreductase (NQO1), which in turn inhibits the mTORC1 pathway and induces autophagy [19]

Nanoparticles that are bound to anti-TNF- antibodies or contain IL-17 inhibitors have shown improved effectiveness in treating psoriasis in animal models (79)

10.1186/s12933-017-0604-9 58 KimR

Consistently, GSH application on leaf 1 significantly induced the expression of defense-responsive genes ( OPR3 , JAZ5 , and JAZ10 ) in leaf 6 (by ~5.6, ~8.6 and ~5.7 folds), which is comparable to that induced by Glu (Fig