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Alterations in anti-oxidative defence enzymes in erythrocytes sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients

Can be used as a spot solution or daily face/body wash

10.1016/j.neuroimage.2014.11.032 167 Snchez-RodrguezI.Temprano-CarazoS.NjeraA.DjebariS.YajeyaJ.GruartA.et al

This combinatorial coding capacity underscores the adaptability of the UPS and its capacity to orchestrate diverse cellular outcomes beyond protein destruction

Abbreviations %: Percentage m: Micrometer ADA: American Diabetes Association ALO: Aloperine ATP: Adenosine triphosphate cAMP: Cyclic adenosine monophosphate CRP: C-reactive protein DKA: Diabetic ketoacidosis DM: Diabetes mellitus DPP-IV: Dipeptidyl peptidase-IV GAD: Glutamic acid decarboxylase GLP-1: Glucagon-like peptide-1 GLUT-4: Glucose transporter type 4 GPx: Glutathione peroxidase GSH: Glutathione HDL: High-density lipoprotein IL-1: Interleukin 1 IRS-2: Insulin receptor substrate-2 LDL: Low-density lipoprotein MAMs: Mitochondria-associated membranes NIDDM: Non-insulin dependent diabetes mellitus nm: Nanometer OS: Oxidative stress PDX-1: Pancreatic and duodenal homeobox-1 PI3K: Phosphatidylinositol 3-kinase PKC: Protein kinase C PPAR-: Peroxisome proliferator-activated receptor- ROS: Reactive oxygen species SOD: Superoxide dismutases STZ: Streptozotocin T1DM: Type 1 diabetes mellitus T2DM: Type 2 diabetes mellitus TNF: Tumour necrosis factor-alpha References Ojo OA, Ibrahim HS, Rotimi DE, Ogunlakin AD, Ojo AB

This flexibility represents both a survival advantage and a therapeutic challenge [20, 21]