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Neurological deficits are associated with the ionic mechanism of lead toxicity due to the ability of lead to replace calcium ions 12

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However, this approach has been limited by the dearth of cancer cell lines that harbor naturally arising dMMR

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Zheng and Conrad, 2020), future investigations should also be directed to understanding the role of POR in these other ferroptosis-associated diseases and the potential applications of POR inhibitors for treating diseases caused by excessive ferroptosis

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