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The strategy involved searching the databases using the following Medical Subject Heading (MeSH) terms: breast cancer, invasive breast cancer, targeted therapy, cancer stages, cancer type, primary therapy, iron overload, iron chelator, deferoxamine, deferasirox, NF-B, and ROS

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(Left: Proportion of studies with low, or high, or unclear concerns regarding applicability

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For hair applications specifically, longer cycles of 12-16 weeks may be appropriate given the slow nature of hair regrowth, followed by 4-6 week breaks