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95 Since the approval of the first antiviral drug, idoxuridine, by the Food and Drug Administration (FDA), over 100 antiviral drugs have been subsequently approved by the FDA

In vitro experiments, including MTT and-H2AX assays, demonstrate their selective cytotoxicity towards ATC cells over normal thyroid cells

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The limit of quantification and limit of detection of Lid were also determined, with the limit of quantification calculated as 2.046 g/mL and the limit of detection as 0.675 g/mL

Biomarker validation The Receiver Operating Characteristic (ROC) curve analysis was performed using MetaboAnalyst 6.0 online tool/ Biomarker analysis

Bishay et al., 2013