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During septicemia, the endotoxin Lipopolysaccharide (LPS) causes systemic inflammation

The dosage of green tea supplementation varied between 200 mg/day (green tea extract) and 9 g/day (green tea leaves), and the duration of intervention ranged from 4 to 48 weeks across selected RCTs

The transmembrane rather than paracellular transport of lipophilic compounds was supported by the demonstration of an inverse association between lipid/water partition coefficient and increased transport rate following calcium chelation, i.e., disrupting intercellular junctions increased the transport of hydrophilic but not of lipophilic small organic molecules [31]