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Is There Ever a Reason to Stop AOD-9604

These sORF produce bioactive peptides, collectively known as mitochondrial-derived peptides (MDP), which have a wide range of physiological functions and can explain how mitochondria communicate within and between cells in a specific disease environment (5)

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When ERK1/2 signaling was inhibited, the beneficial effects of BPC-157 on wound closure were significantly reduced, confirming this pathways importance in the peptides mechanism of action

These effects were dose-dependent, with the 54 mg dose (substantially higher than standard protocols) showing increased GI-related events

Chien KL, Lee BC, Hsu HC, Lin HJ, Chen MF, Lee YT