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DOI:10.3389/fphar.2021.627533

In patients with pre- existing seizure activity, an increase in seizure frequency and/or severity has been reported

and Guo, M, "Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin", Nature 441: 1162-1166 (2006)

Muscle cramps predominantly afflict the lower limb muscles, notably the calves and feet, though the fingers and hands may also be susceptible (4, 8, 26)