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In the absence of a stressor, DMSO inhibited upstream of unfolded protein response or ER stress pathway, such as phosphorylation of p-EIF2AK3, EIF2S1 and the expression of ATF4, ATF6, p-AKT1 and p-MTOR in a time- and dose-dependent manner (Fig

Dual luciferase reporter assay was performed using Dual Luciferase Reporter Assay System (Promega)

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Supporting that pool is thought to be relevant to mitochondrial efficiency a connection that overlaps with the broader longevity and cellular health research base