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Avoiding strenuous exercise, excessive heat exposure, and facial massage for 24-48 hours helps ensure optimal settling and the best possible results

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then 5000 mcg monthly for maintenance Monitoring : You cant really overdose on B12, as its water-soluble, but I always recommend doing the initial test and retesting three months later, to track and monitor your progress

Human clinical data, however, remains extremely limited

Annals of the New York Academy of Sciences (2010) 9

Bottled water is no better