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Brobert GP

55 The two major inherited disorders are those involving the metabolism of the dibasic amino acids lysine and ornithine and those involving the metabolism of organic acids, such as propionic acid, methylmalonic acid, isovaleric acid, and others (see Chapter 58)

The former should work better for gastrointestinal health support, while the latter might provide a greater level of joint and muscle support

Zinc's role in digestion and metabolism is also fundamental to the optimal absorption and utilisation of nutrients

Furthermore, anticholinergic medications, such as trihexyphenidyl, are used also in PD management but struggle to effectively cross the BBB and often exhibit non-specific binding, leading to undesirable peripheral effects such as dry mouth and cognitive impairment, particularly in elderly patients

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