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Growing preclinical evidence demonstrates that these nanoparticle-based systems can effectively deliver diverse therapeutic agents, such as anti-inflammatory compounds, antioxidants, or regenerative factors, directly to the specific renal cells and structures implicated in maladaptive inflammation and fibrosis

The follicular environment is infiltrated by various immune cells, such as T cells, B cells, macrophages, and dendritic cells, which secrete cytokines and growth factors that affect follicular growth, selection, and atresia [30]

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