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Mohammadi et al

This is irreversible degradation

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Foundation for Peripheral Neuropathy

[58] Functionally, the 5-HT 2A receptor is a G protein-coupled receptor (GPCR) that primarily signals through the phospholipase C (PLC) pathway, leading to the production of inositol triphosphate (IP3) and diacylglycerol, but it can also activate other signaling cascades such as arachidonic acid and 2-arachidonylglycerol pathways