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The resulting lack of IDO2 activity hinders tryptophan conversion to kynurenine

10 A number of key components were evaluated, including the randomization process, deviations from the intended interventions (blinding of the participants), measurement of the outcome (blinding of the investigator), and missing outcome data

As one of the important mediators of RA, it can induce angiogenesis, promote FLSs migration and cartilage destruction, and inhibit the apoptosis of synovial cells (211)

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