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Per- and poly-fluoroalkyl substances (PFAS) have been shown to reduce circulating thyroid hormone levels by interfering with intracellular signaling cascades, like mitogen-activated protein kinase (MAPK) pathway, which can alter thyroid hormone production, secretion, and cellular responses (93)

therefore, all of the orbitals are filled so d-d transitions cannot occur here

Published December 11, 2024

This should also concern an in-depth analysis of the mechanism of action, including NO as the target most affected by the peptide, as well as the off-targets and their possible effects