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JAMA 312:26682675

In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy

However, according to Merck Manual, Intestinal parasitism commonly complicates feline panleukopenia, especially in shelter environments, so use of anthelmintics (eg, fenbendazole, 50 mg/kg, PO, once daily for 5 days) is an important consideration and can be started once vomiting is controlled. Antibiotics (Symptomatic and Direct Contact) Convenia has always been the antibiotic of choice for me when dealing with panleukopenia

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TNF and ROS Crosstalk in Inflammation

In addition to VEGF, fibroblast growth factor 2 (FGF-2) and platelet-derived growth factors (PDGFs) significantly contribute to tumor neovascularization and vascular remodeling 17,18,19,20,21