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Studies have demonstrated that lipid peroxidation products can aggravate oxidative stress and promote cell death by activating various intracellular receptors, enzymes, and signaling pathways ( 2.3 Antioxidant pathways and ferroptosis Ferroptosis is an iron-dependent, non-apoptotic form of cell death, typically accompanied by a significant increase in intracellular ROS levels

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doi:10.1515/hmbci-2020-0041 Panda C, Komarnytsky S, Fleming MN, et al