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Understanding tesofensine's unique mechanism and risk profile helps determine if this powerful but controversial weight loss compound merits consideration despite its FDA rejection and safety concerns

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Coimmunoprecipitation (Co-IP) Cells were washed with PBS and lysed on ice for 30 min with IP lysis solution (Beyotime) supplemented with protease and phosphatase inhibitors (Thermo Fisher Scientific)

2006 Jan-Feb;21(1):113-9