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Within neonatology, although the methodological rigor of available studies is frequently limited (397, 398), emerging evidence suggests that specific probiotic strains may confer protection against necrotizing enterocolitis in preterm infants

Concurrently, standardizing the assessment of metabolic assessments is critical: the hyperinsulinemic-euglycemic clamp should be universally prioritized as the gold standard for evaluating insulin sensitivity to minimize bias arising from methodological heterogeneity

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Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions

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