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542 Although tau protein aggregation and beta-amyloid protein (A) accumulation play central roles in the pathophysiological hypothesis of AD, the potential role of metal overload, subsequent oxidative stress, and tissue damage cannot be ignored

Compatible solutes contribute to heat resistance and ribosome stability in Escherichia coli AW1.7

High ATP demand, in combination with dysfunctional mitochondria, make these neuron groups more sensitive to degeneration (Wang and Michaelis, 2010)

The various metallic NPs used to treat PDs are gold (AuNPs) and silver nanoparticles (AgNPs) (103)

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Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human