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Zapf, J., Hauri, C., Waldvogel, M

revealed the importance of heme oxygenase 1 (HO-1) where a significant rise in HO-1 synthesis was observed in SOD1-G93A mice treated with DATS compared to animals that received a placebo

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Norepinephrine and epinephrine are relatively small, highly polar molecules with primary amine groups that are fully protonated at physiological pH and show markedly negative distribution coefficients in aqueous buffer, indicating a strong preference for the aqueous phase 26,27,28,29,30

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