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[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Bodmer W.F., Bailey C.J., Bodmer J., Bussey H.J., Ellis A., Gorman P., Lucibello F.C., Murday V.A., Rider S.H., Scambler P., et al

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With the exception of the poorly active hybrid protein ScGrx8 from yeast 11 , the second cysteine residue of enzymatically active Grx is dispensable for the reduction of glutathionylated substrates and the low-molecular weight model substrate bis(2-hydroxyethyl)disulfide (HEDS) 15,16,17,18,19,20,21,22,23,24,25