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CD38 as theranostic target in oncology Journal of Translational Medicine Springer Nature Link 5 Amino 1MQ blocks an enzyme called NNMT, and the mechanism is real, but NNMT overexpression does not track body fat. It tracks insulin resistance. Non diabetic individuals at BMI 33 had normal NNMT. And A Potent and Specific CD38 Inhibitor Ameliorates Age Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline: Cell Metabolism Biological Functions and Therapeutic Potential of NAD+ Metabolism in Gynecological Cancers Frontiers CD38: A Significant Regulator of Macrophage Function CD38 as a therapeutic target for MM
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