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This may partly explain the dramatic increase in Syn-S129p levels from ~4% under physiological conditions to ~90% in pathological conditions 5,31,32,87,88

While B12 is essential and generally safe in appropriate doses, problems can arise when its taken in excess or combined with certain medications, especially if kidney function is already compromised

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Protective effects of smyrnium cordifolium boiss essential oil on pentylenetetrazol-induced seizures in mice: involvement of benzodiazepine and opioid antagonists