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These mouse studies appear relevant to human disease, as a large number of studies have shown that polymorphisms in PON1 are associated with increased risk for atherosclerosis (265)

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Additionally, the cost of these medications can pose a significant barrier to long-term treatment adherence ( 2.1.4 Cannabinoids Since the early 1970s, research has explored the effects of cannabinoids (CB) on glaucoma (48, 49)

The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids