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To assess the suppressing effect of VGB4 on PI3K/AKT and MAPK/ERK1/2 signaling pathways, western blot analysis of AKT, p-AKT, ERK1/2 and p-ERK1/2 were performed both in vitro (HUVECs) and in vivo (4T1 tumor tissue sections)

The mouse line, which contains loxP elements in the introns flanking exon 2 of the Gata6 gene, was bred with mice expressing the Cre recombinase under the control of the endothelial-specific VE-cadherin promoter (Jackson Laboratory)

a, b Sime, L., Hopcroft, P

doi: 10.1007/s00018-023-04932-3 66 SenKPatiRJhaAMishraGPPrustySChaudharySet al

These conditions are characterized by an imbalance of good and bad microbes in the microbiome, which can contribute to digestive issues and inflammation