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Galimberti D, Scarpini E, Venturelli E, Strobel A, Herterich S, Fenoglio C, Guidi I, Scalabrini D, Cortini F, Bresolin N, Lesch K-P, Reif A (2008) Association of a NOS1 promoter repeat with Alzheimers disease

Epitalon is a tetrapeptide (Ala-Glu-Asp-Gly) that activates transcription of the hTERT gene, the catalytic component of telomerase

Inflammatory markers corroborate these molecular shifts: testosterone elevates IL1R1 expression, indicative of pro-inflammatory signaling, while suppressing anti-inflammatory IL-10

In addition, eNAMPT may act biochemically by metabolizing extracellular nicotinamide into NMN, which may diffuse into the cell, restoring the parental phenotype