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Mechanism Genetics and epigenetics Gene-environment interactions in allergy diseases Allergic disease is a complex disorder, whose etiology and development may involve genetic and environmental factors

The glycaemic response to sepsis is well-recognized and has been clearly linked to upregulation of glycolytic pathways in immune cells with involvement of cellular energy sensors such as mechanistic target of rapamycin (mTOR) and AMPK (228, 229)

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They operate on separate pathways and do not directly interact at the receptor level

10.1080/00926230390155104 [DOI] [PubMed] [Google Scholar] Stough C., Pase M., Cropley V., Myers S., Nolidin K., King R., et al

One notable observation is that ABCB6 exhibits the differential requirement for GSH as a cofactor depending on the substrate type (Fig