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Heme oxygenase-1 expression in endothelial cells leads to decreased expression of vascular cell adhesion molecule-1 (VCAM-1) as well as the expression and release of chemokines and proinflammatory cytokines such as CC-chemokine ligand (CCL)2, also known as MCP-1 (Sacerdoti et al., 2005)

A key contributor to this work was Chandan Sen and colleagues who described the effects of varying levels of glutathione on exercise responses and the effects of exercise on glutathione content and redox status (351, 352)

In contrast to the previous studies [7], one of our innovative findings is that TBI gives rise to an elevated level of Fe 2+ in the serum, and its discrepancy may have something to do with different investigative time points

As mentioned earlier, BisAbs contain engineered disulfide bonds which make this type of antibodies more susceptible to aggregation due to disulfide bond mispairing 4

doi: 10.1016/j.jaci.2003.10.050

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