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Autonomous diseases are typically more prevalent in women than in men (Quintero et al., 2012)

10.1083/jcb.17.2.375 84 FeigheryL

Hypertension is defined as systolic blood pressure (BP) of 140 mmHg or higher and diastolic blood pressure (BP) of 90 mmHg or lower, affecting 31.1% of the worlds adult population, or 1.38 billion people, in 2010 (108)

Mechanism-level data show GHK-Cu enlarges hair follicles and prolongs the anagen phase in rodent models

it is effective on both pruritus and cholestasis in PFIC, potentially being a disease-modifying intervention