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Ethics approval and consent to participate Use of cell lines for this study was approved by the Ethics Committee of the Graduate School of Medical Sciences, Kyushu University

10.1016/j.yjmcc.2013.11.015 J

In addition, the glutathione level was induced by DMB administration in the colon ( Figure 3C )

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A second messenger response, e.g., signal transduction or pH changes, is then measured to determine whether the potential compound activates or inhibits the receptor