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Signals from the innate immune system typically initiate immune responses in the skin, while cells and cytokines from the adaptive immune system sustain inflammation, ensuring effective defense against pathogens

RN: Writing review & editing, Writing original draft, Validation, Supervision, Funding acquisition, Formal analysis, Conceptualization

Theyre known for their strong antioxidant and anti-inflammatory properties

broader NO-system interplay summarized in review (Sikiric 2014)

Studies indicate that abnormalities in iron metabolism in gastric cancer cells, such as upregulation of TFR1 and dysregulated ferritin storage, significantly promote ferroptosis sensitivity, while ferroptosis inducers (such as Erastin and RSL3) can enhance chemotherapy sensitivity and reverse resistance by inhibiting GPX4 or system Xc-

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