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The war against RA has only just begun

Psychiatry 8 , 222 (2018)

To investigate the targeting mechanism of cPLT, inflamed cells were pre-incubated with an excess of free anti-vWF antibody for 30 min to block the vWF binding sites, followed by the addition of DiO-labeled cPLT as described above

While TPOAb reflects an adaptive immune response, TgAb is more closely linked to innate immunity, representing distinct arms of the autoimmune reaction