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Li W, Feng G, Gauthier JM, Lokshina I, Higashikubo R, Evans S, et al

Cluster RCTs : Instead of randomizing individuals, whole groups (e.g., schools, clinics, teams) are randomized, which is useful when individual randomization is impractical or risks contamination between groups

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In the present study, a 6-h application duration was chosen to ensure better compliance

This table draws from various studies emphasizing that while supplements offer targeted benefits, whole foods are often superior, with risks outweighing pros in some cases without medical advice

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