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Roll, do not shake: Gently roll the vial between your palms until fully dissolved

doi:10.1038/25354

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10.1016/0162-0134(92)84013-d [DOI] [PubMed] [Google Scholar] Apostolopoulos V., Bojarska J., Chai T

Upon GRK phosphorylation, the GPCR's affinity for -arrestin (-arrestin-1/2 in most tissues) is increased, at which point -arrestin may bind and act to both sterically hinder G-protein coupling as well as initiate the process of receptor internalization through clathrin-mediated endocytosis

LHCGR Binding and Biased Agonism Research using BRET and FRET technologies in living cells confirmed that hCG and LH differentially promote cell responses mediated by the LHCGR revealing divergences in potency, efficacy, and kinetics